- In the U.S., there are at least 42,000 cases across all 50 states, plus Puerto Rico, the U.S. Virgin Islands and Washington D.C., and at least 515 have died from the virus, according to CNN.

- Officials in multiple states including New York, California, Ohio, Illinois, Indiana, Louisiana, New Jersey, Michigan, Washington and Connecticut are ordering residents to stay at home.

- The U.S. National Guard has been activated in three of the hardest hit states: California, Washington and New York.

- Vice President Mike Pence and his wife tested negative for coronavirus on Saturday, while Sen. Rand Paul announced Sunday he had tested positive.

- The White House announced Monday that First Lady Melania Trump tested negative for the coronavirus.

President Donald Trump said Monday that he wants to reopen the country for business in weeks, not months.

"We can’t have the cure be worse than the problem," Trump told reporters at a press briefing, echoing a midnight Sunday tweet. "We have to open our country because that causes problems that, in my opinion, could be far bigger problems."

Trump acknowledged there were trade-offs. "There's no question about that," but claimed — without evidence — that, if closures stretch on for months, there would be “probably more death from that than anything that we're talking about with respect to the virus.”

US death toll surpasses 500 as cases spike nationwide

The battle against coronavirus has intensified across the country as more workers are laid off, medical supplies dwindle, and states enact new rules to get Americans to stay home.

"I want America to understand — this week, it's going to get bad," U.S. Surgeon General Jerome Adams told NBC's "Today" show Monday.

"We really, really need everyone to stay at home. I think that there are a lot of people who are doing the right things, but...we're finding out a lot of people think this can't happen to them."

More than 42,000 Americans have been infected with coronavirus across all 50 states, and at least 515 people have died.

"If we do nothing, cases will increase fivefold," said Dr. Joneigh S. Khaldun of the Michigan Department of Health.

Trump has activated the U.S. National Guard in three of the hardest-hit states — California, Washington and New York. Around half of all U.S. cases — 20,875 — are in New York state.

Trump said those National Guard units will remain in the command of the states' governors.

Across the country, multiple states have issued stay-at-home orders that are either in effect or will take effect this week. By Wednesday, more than 126 million Americans will be subject to those new rules.

Gov. Ron DeSantis said Monday that he will sign an executive order that will force anyone who travels from New York or New Jersey to Florida to self-isolate for two weeks immediately after they land in the state.

It's all in an effort to control the deadly virus and prevent a catastrophic overload of the U.S. health care system.

Senate fails to pass coronavirus aid bill

Senate Democrats on Monday blocked advancing a coronavirus economic stimulus bill when a procedural vote failed to get to the 60 votes needed to pass.

It was the second time in two days Democrats blocked the measure as talks over the giant bill continue.

The vote tally was 49-46 with a largely party line vote.

Senate Democrats lined up against the measure – just as they did yesterday when the first attempted procedural vote failed – as they argue that Majority Leader Mitch McConnell should not be holding what they have called “arbitrary” votes while negotiators are still attempting to reach a bipartisan deal.

The failed vote is sure to incense Republicans, who have been criticizing Democrats all morning and accusing them of holding up efforts to move the package forward, and ratchet up tensions as lawmakers continue to hold talks on a stimulus package.

Stay at home orders

California, Illinois, New York and New Jersey were already under stay at home orders over the weekend. Connecticut, Indiana, Michigan, Washington and West Virginia joined the growing number of states ordering people to stay home, with a few exceptions.

Massachusetts and Maryland said all non-critical businesses must shut down their physical workplaces. And Virginia, like Kansas, has canceled all classes for the rest of this school year.

The orders encourage social distancing measures but make exceptions for people to leave their homes for things like buying food, picking up medicine and going to work for essential jobs. Some encourage being outside and active — as long as it isn't done in groups.